The city with the highest murder rate per 100,000 people in the U.S. is St. Louis, Missouri, with a rate of 69.4. Following St. Louis, the next highest rates are found in Baltimore, Maryland (51.1), New Orleans, Louisiana (41.2), and Washington, D.C. (39.6). The list continues with Detroit, Michigan (39.1), Memphis, Tennessee (29.0), Birmingham, Alabama (26.5), Kansas City, Missouri (24.4), Cleveland, Ohio (23.9), and Philadelphia, Pennsylvania (23.1).